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Our Purpose

Orthopaedics & Robotics

Smith+Nephew's Orthopaedics portfolio includes an innovative range of hip and knee implants used to replace diseased, damaged or worn joints, robotics-assisted and enabling technologies, and services that empower surgeons. It also includes trauma products used to stabilise severe fractures and correct bone deformities. In addition to trauma products used to stabilize severe fractures and correct bone deformities. The CORI Surgical System with Real Intelligence software offers broad capabilities and an expanding range of joint reconstruction indications.

To submit a proposal, navigate to the appropriate study type at the bottom of the page and click the ‘Submit Proposal’ button within.
Submit Idea

Smith+Nephew recognizes the importance of supporting Clinical Activities that lead to a greater understanding of our therapies and their potential applications, improved patient care, and new ideas for further research.​

We accept unsolicited requests for research grants from academic and community-based clinician-scientists who are interested in conducting their own activity.

All investigators who are awarded support must provide Smith+Nephew with ongoing study updates and final deliverables.

We welcome proposals for a variety of clinical activities including Investigator Initiated Studies (IISs), Manuscript and Abstract Preparation activities, Collaborative Clinical Research projects and Real World Evidence activities. Click the tiles at the bottom of this page to learn more about each and proceed with proposal submission.

As the sponsor of the study, the investigator and/or institution assume responsibility for all aspects of the study.

  • Study design and protocol development
  • Institutional and regulatory approvals and reporting
    • IRB/EC approval
    • Registration on ClinicalTrials.gov
    • IND/IDE application submission
    • Serious adverse event reporting to the FDA, IRB, and Smith+Nephew
  • Study conduct in accordance with ICH GCP Guidelines and all applicable local and regulatory requirements
  • Communication of all ongoing study updates (see section below)
  • Reconciliation and closeout reporting (see section below)
  • Clinical study report submission within 90 days of study completion
  • Dissemination of study results in a peer-reviewed publication and/or at a medical meeting within 6 months of study completion

The Investigator needs to complete a study proposal and budget, these will be provided once you have selected the relevant study type below.

Support is awarded based upon scientific merit, as well as alignment with our research areas of interest and availability of resources. We may provide research grants in the form of funding, and/or study product.

It can take approximately 6 to 8 weeks for a proposal to be approved, but may be longer in certain circumstances. Once submitted, a review of your proposal will take place including initial proposal and budget review, before moving on to an in-depth departmental review.

Once approved the contracting process can take up to 3 months depending on the Institution’s internal contracting process. The Investigator should not commence work on a proposal until a fully executed contract is in place. All contracts are with the Institution not the Investigator.

S+N will provide all or partial funding for any IIS that has been approved. S+N would prefer to provide funding to cover the device cost, rather than provide devices, but it can be done if absolutely necessary. Investigators can not be paid directly. All funding is to the institution responsible for and housing the patient data. No exceptions.

The Investigator must notify Smith+Nephew of the following updates for ongoing studies:

  • Amendments to the study protocol
  • Regulatory re-approvals
  • Serious adverse events reports
  • Achievement of study milestones related to milestone payments
  • Subject enrollment progress (e.g., first subject in, last subject in, last subject out, etc.)

A clinical study report (CSR) is required within 90 days of study completion. The CSR should be written in accordance with the ICH Guidance for Structure and Content of Clinical Study Reports. Please refer to our guidance document here. A CSR template is provided for you here.

Submission for publication in a peer-reviewed journal is required within 6 months of study completion. All publications should comply with recognized ethical standards concerning publications and authorship, including the Uniform Requirements for Manuscripts Submitted to Biomedical Journals, established by the International Committee of Medical Journal Editors.

Smith+Nephew at least 30 days in advance of submission for publication. Additionally, we must receive evidence of submission for publication no later than 6 months following completion of the study. For research support that includes funding, the final milestone payment is dependent on submission for publication or presentation of study results.

Benefits to you: Funding support for research interests, Opportunities to collaborate with peers by participating in multi-center S&N sponsored studies and Med Ed opportunities to attend advanced courses/conferences

Benefits to S+N: Evidence to guide strategic direction for the life of the product, Clinical data to support product claims & meet regulatory requirements

Orthopaedic Reconstruction

Knee Reconstruction 

  • Medial Dish insert (JOURNEY◊ II CR)
  • Articular Stabilized Insert (JOURNEY II BCS)
  • CONCELOC Tibia and / or Patellae

Hip reconstruction 

  • OR3O Dual Mobility
  • ABLE Approach
  • RI.HIP Navigation

Extremity Reconstruction

  • TITAN Total Shoulder System
  • CADENCE Total Ankle System
  • Salto Talaris
  • Pyrodisk, CMC, PIP, MCP, sMCP arthroplasty
  • Freedom Wrist Arthroplasty System
  • CMRH and MRH
Improvement in patient-related outcomes, including health economic outcomes, compared to standard care

Robotics & Enabling Technologies/Digital Health

  • CORI Surgical System
  • CORI Digital Tensioner
  • RI.Insights

Orthopaedic Trauma


TRIGEN META-Nail Antegrade Tibia
TRIGEN META-Nail Retrograde Femoral
TRIGEN Humeral Nail

Research questions including:

  • Biomechanic Stability and Gait
  • Return to Function
  • Time to Union
  • Health Economics

Plate & Cable Systems

  • EVOS Plating Systems
  • D-RAD
  • VLP MiniMod
  • ACCORD Cable System
  • Cannulated Screws
Improvement in patient-related outcomes, including health economic outcomes, compared to standard care

External Fixation and Limb Restoration

  • Taylor Spatial Frame
    • TSF ALLY
  • Maverick External Fixation
  • lIzarov External Fixator
  • Modular Rail System
Improvement in patient-related outcomes, including health economic outcomes, compared to standard care

External Fixation research questions including but not limited to

  • Dynamization strategies and protocols
  • Coatings on fixation
  • Accuracy of automated mounting parameters and impact on total residuals
  • Health economic impact of limb salvage versus amputation
  • Optimizing rate and rhythm in circular fixation
  • Evaluation of Return to Function Outcomes such as range of motion, return to mobilization, and/or early weight-bearing tolerance
  • Special Populations
Improvement in patient-related outcomes, including health economic outcomes, compared to standard care

The following study types may be considered for support:

  • Prospective or Retrospective clinical studies involving Smith+Nephew productss 
  • Non-interventional research, such as epidemiology or outcomes studies, where the focus is on scientific understanding of the disease

We do not provide support for the following: 

  • Proposals that are not aligned with our current areas of interest 
  • Proposals that are conditioned upon past or future prescriptions or purchases of Smith+Nephew products 
  • Requests that create a conflict of interest for Smith+Nephew 

  • Investigator Initiated Studies

    A clinical study designed and initiated by an investigator, whereby S+N provide funding (monetary or medical devices) but do not act as Sponsor.  Any type of study design (qualitative/quantitative) can be an IIS as the design of the study and proposal submitted to S+N for consideration comes directly from the Investigator/HCP. 
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  • Collaborative Research

    A clinical activity whereby the design and/or conduct of said activity is done jointly to collaborate on fulfilling the objectives of the activity.  

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  • Manuscript, Abstract, & Publication

    Any type of clinical research whereby an investigator/HCP approaches S+N to ask for assistance (monetary or resource) to analyse and/or write up their existing data (external to S+N) for publication or as a conference proceeding.

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  • Real World Evidence

    The collection or extraction of data from routine patient treatment, that is available within the patient medical record (paper or EMR) or at the time treatment/procedure.

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  • Non-Clinical Investigator Initiated Studies

    Well controlled and carefully documented laboratory research studies of new and existing products and technologies are an integral part of the product development and quality assurance processes as well as technique exploration and procedure development.

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We design and manufacture technology that takes the limits off living. We support healthcare professionals to return their patients to health and mobility, helping them to perform at their fullest potential.
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Trademark of Smith+Nephew. Product information is for educational purposes only, and not all products or indications are licensed in every country.